logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name ERBB2 siRNA
ncRNA Category siRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line RPE cell line ARPE-19
Methods siRNA transfection, cell viability assay, qPCR, immunoblot
Expression pattern associated
Functional description ERBB2 may play an important role in modulating autophagic RPE cell death during oxidative stress. ERBB2 knockdown reduced reactive oxygen species (ROS) production in ARPE-19 cells during oxidative stress.
PubMed ID 30870514
Year 2019
Title ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.