ncRNA name | ERBB2 siRNA |
ncRNA Category | siRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | RPE cell line ARPE-19 |
Methods | siRNA transfection, cell viability assay, qPCR, immunoblot |
Expression pattern | associated |
Functional description | ERBB2 may play an important role in modulating autophagic RPE cell death during oxidative stress. ERBB2 knockdown reduced reactive oxygen species (ROS) production in ARPE-19 cells during oxidative stress. |
PubMed ID | 30870514 |
Year | 2019 |
Title | ERBB2-modulated ATG4B and autophagic cell death in human ARPE19 during oxidative stress. |
Drug-related ncRNA | NO |
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